Over the past few years, a new class of medications has transformed the treatment of obesity. Drugs like Ozempic, Wegovy and Mounjaro work primarily by reducing appetite, helping people eat less and feel full sooner. Their success has demonstrated something important: Body weight is biologically regulated, and targeting the right biological pathways can lead to meaningful weight loss that can help transform lives.
But appetite is only half of the equation. Your weight reflects a balance between the calories you consume through your diet and the energy you expend through movement, exercise and maintaining basic cellular function. While recent therapies have focused on controlling energy intake, scientists are increasingly turning their attention to the other side of the ledger: the tissues that burn energy.
