The parent company of Facebook, Instagram and WhatsApp, it to cut around 10,000 jobs globally - just four months after it laid off 11,000 workers.
Meta’s founder and boss, Mark Zuckerberg, yesterday told staff in a company blog the company is also looking to ditch about 5,000 open job vacancies as part of his Year Of Efficiency push to slash costs and restructure the firm.
The Silicon Valley firm will first cut the size of its recruiting team, with staff in this division expected to be told where the cuts will be made today.
It will be followed by layoffs in its tech groups in late April, before taking the axe to roles across its business groups in late May.
Mr Zuckerberg said: "This will be tough and there's no way around that.
"It will mean saying goodbye to talented and passionate colleagues who have been part of our success."
It follows Meta's announcement last November that it was cutting 11,000 jobs out of its 87,000-strong global workforce.
Those cuts were expected to mean as many as 650 job losses in the UK and around 350 at risk in Ireland.
Meta said yesterday it would not provide a breakdown of where the latest job cuts would come from worldwide.
Mr Zuckerberg added: "I've said that part of our work will involve removing jobs - and that will be in service of both building a leaner, more technical company and improving our business performance to enable our long-term vision."
The California-based firm last month posted lower profits for the final three months of 2022 after it took a hit from a slump in the online advertising market, wider economic woes and increasing competition from rivals such as TikTok.