Dietary Fat Raised a Brain Protein in Male Mice but Not Females, and an Obesity Drug Then Worked Less Well

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When researchers at Osaka Metropolitan University placed a bottle of soybean oil next to the regular chow in a mouse cage, something measurable occurred within a small cluster of appetite-regulating neurons in the male mice' brains. A mitochondrial protein called OPA1 climbed. In the females, it did not.