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Madona Azar, Associate Professor of Medicine, UMass Chan Medical School

Diabetes and obesity can damage the liver to the point of failure – but few people know their risk of developing liver disease

diabetes Disease Obesity Cancer United States Weight Loss

Insulin resistance links MASLD to several other metabolic diseases. Kateryna Kon/Science Photo Library via Getty Images

Liver disease is frighteningly common worldwide.

Metabolic dysfunction-associated steatotic liver disease, or MASLD, is an umbrella term describing conditions related to a buildup of fat in the liver. Formerly known as nonalcoholic fatty liver disease, this condition affects 1 in 4 people worldwide. Among those with type 2 diabetes, insulin resistance, obesity or all three, the prevalence of MASLD increases to 3 in 4 people.

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