Christina Applegate has announced she has retired from on-screen acting after being diagnosed with Multiple Sclerosis.
The actress, 51, is best known for her roles in Anchorman alongside Will Ferrell and Married With Children, but has revealed she won't step in front of the camera for another acting role.
However, she refused to let the decision get her down and she confessed her gratitude for the successful career she had and being able to work with Linda Cardellini again in her final role on Dead to Me.
