Christina Applegate stepped away from the Hollywood spotlight in March 2026 to prioritize her health after six years of debilitating symptoms attributed to multiple sclerosis (MS).
When she returned to her MeSsy podcast on Tuesday, October 20, listeners expected an update on her well-being and how she had been coping during her time away.
Instead, the conversation took an unexpected turn when Applegate revealed that she had been misdiagnosed.
