A study has raised a question that many women would understandably want answered: could hormone replacement therapy (HRT) protect against dementia? The research found that women who had used HRT were less likely to receive a dementia diagnosis during follow-up, particularly if they had undergone surgery involving their reproductive organs. But the results do not establish that HRT caused the difference.
The researchers analysed data from 183,450 postmenopausal women in the UK Biobank, followed for an average of 13.3 years. During that period, 3,948 received a dementia diagnosis, including 1,993 diagnosed with Alzheimer’s disease.
