
Bread and other refined carbohydrate foods have long been linked to weight gain, but new animal research suggests the story is more complex than "too many calories." In a controlled mouse study, a carb‑heavy wheat flour and bread–style diet altered metabolism, reduced energy expenditure, and increased fat gain even when total calorie intake did not rise.
This raises questions about how specific carbohydrates influence the body's energy systems and why some foods may be more fattening than their calorie counts suggest.