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LiveScience
LiveScience
RJ Mackenzie

Brain aging results from a loss of control over how genes are regulated, mouse study suggests

Human brain digital illustration.

Aging may "erase" the epigenetic markers that control gene expression in the brain, and this may snowball to cause unintended consequences, a new mouse study suggests.

Tiny chemical messages attached to our genetic code, called epigenetic markers, change with age in many organs of the human body, leading to the development of ''aging clocks'' that track the loss of these epigenetic tags at specific locations in the genome. However, data from far more locations, particularly the brain, are needed to identify aging processes that could be slowed or reversed.

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