Thomas Partey is out of Arsenal’s huge Premier League title clash with Manchester City tonight.
The blow comes as long-term absentees Gabriel Jesus, Mohamed Elneny, Emile Smith Rowe and Reiss Nelson are also not available for the Gunners.
Mikel Arteta has named an unchanged team for the past six Premier League games, but calls upon Jorginho here to replace Partey in his line-up against City.
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There is also a change at right-back, as Takehiro Tomiyasu comes into the side and Ben White drops to the bench.
Leandro Trossard was pushing to start in place of Martienlli after he scored off the bench against Brentford last weekend, but he is among the substitutes again.
“For us it is more about the performances and as well what players have given us to take us to the position that we are in today,” said Arteta earlier this week.
“They deserve the opportunities. Obviously we are looking to move players and give players opportunities that they deserve.
“You talked about Leo, but we talk about anybody that has had minutes in this League. There will be changes and it will happen very soon.”
Arsenal XI: Ramsdale, Tomiyasu, Saliba, Gabriel, Zinchenko, Odegaard, Jorginho, Xhaka, Saka, Nketiah, Martinelli
Subs: Tierney, White, Kiwior, Holding, Trossard, Vieira, Nelson, Turner, Cozier-Duberry