Mikel Arteta could be forced to go with an untested centre-half partnership after Gabriel's injury blow.
Arsenal have already been having to deal without William Saliba, who has been missing since mid-March. His absence has coincided with a dip in form which has hampered their title hopes. Rob Holding had come in alongside Gabriel, but the Brazilian was forced off late in the Chelsea win.
Arteta has not appeared optimistic about the defender's chance of a swift recovery, which would limit his options and leave him with little choice but to pair Holding and Jakub Kiwior at the heart of defence, at least for a short period.