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LiveScience
LiveScience
Kristina Killgrove

Ancient-DNA analysis solves 500-year-old mystery of what killed 2 Medici brothers

Researchers in green scrubs study a human skeleton on a table.

Two brothers from the wealthy and powerful Medici family died of malaria and were not poisoned as a rumor had suggested, archaeologists have confirmed based on a DNA analysis of the brothers' skeletons. The analysis also revealed a unique, mutated strain of malaria that may hold the key to understanding the evolution of the disease in Europe.

The Medici family rose to power in the 15th century by creating the largest bank in Europe. The family used their extraordinary wealth to fund Renaissance artists and to start a political dynasty that eventually included numerous dukes, four popes and two queens of France.

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