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Martin Whyte, Associate Professor of Metabolic Medicine, University of Surrey

An oral weight loss pill has just passed early trials with promising results – here’s how it works

Numerous companies are working on developing weight loss pills that would have similar effects as injectable drugs currently on the market. Ljupco Smokovski/ Shutterstock

The arrival of GLP-1 analogue drugs (such as Wegovy) marked a huge shift in the weight loss drug market. These drugs have been shown to lead to significant weight loss in users – as much as 15% or more of their body weight in clinical trials. For this reason, demand for weight loss drugs has skyrocketed worldwide.

Most of the GLP-1 analogue drugs on the market are taken as a weekly injection under the skin. But many companies are now working on translating these drugs into a form that can be taken orally, as a pill.

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