Incumbent Sen. Lisa Murkowski (R) defeated Kelly Tshibaka (R), and Patricia Chesbro (D) in the general election for U.S. Senate in Alaska on November 8, 2022.
The three candidates advanced from the top-four primary held on August 16, 2022, the first time Alaska used such a system in a Senate race since voters there approved it in 2020. All candidates, regardless of party affiliation, ran in a single primary. Murkowski, Tshibaka, Chesbro, and Buzz Kelley (R) received the most votes and advanced to the general election, where the winner was decided using ranked-choice voting.
On September 12, 2022, Kelley withdrew from the race and endorsed Tshibaka. His name still appeared on the ballot.
