An AI model has just created new viruses that never existed in nature. According to a New York Times report, researchers trained a genomic AI model to design complete DNA sequences for viruses, then chemically built the results and watched some come to life. Of 285 AI-generated viral genomes tested, 16 successfully assembled into functioning viruses capable of infecting bacteria and reproducing.
In the study, published in the journal Science, researchers at Stanford University and the Arc Institute trained genomic AI models called Evo on trillions of nucleotides — the individual building blocks of DNA found in every living organism — allowing it to learn statistical patterns in how biological DNA is arranged. Much as a language model learns which combinations of words tend to make sense, Evo learned which combinations of nucleotides tend to produce biologically meaningful sequences.