An eye scan of a 52-year-old woman caught something that does not appear among previously reported findings in amyloidosis of the eye: bright material erupting from tiny blood vessels in the retina and shooting into the gel that fills the eye, like a geyser. The woman has transthyretin amyloidosis, a disease in which a misfolded protein builds up in the body's tissues.
The image appears in a recent report in JAMA Ophthalmology titled "Geyserlike OCT Sign in Transthyretin Amyloidosis," by Luca Cimino, Luca De Simone and Riccardo Genovese. It is striking on its own, but it also points to a less familiar side of the disease: the eye can become a stubborn site of protein buildup.
