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Bill Sullivan, Professor of Microbiology and Immunology, Indiana University

A common parasite can decapitate human sperm − with implications for male fertility

_Toxoplasma_ can infiltrate the reproductive system. wildpixel/iStock via Getty Images Plus

Male fertility rates have been plummeting over the past half-century. An analysis from 1992 noted a steady decrease in sperm counts and quality since the 1940s. A more recent study found that male infertility rates increased nearly 80% from 1990 to 2019. The reasons driving this trend remain a mystery, but frequently cited culprits include obesity, poor diet and environmental toxins.

Infectious diseases such as gonorrhea or chlamydia are often overlooked factors that affect fertility in men. Accumulating evidence suggests that a common single-celled parasite called Toxoplasma gondii may also be a contributor: An April 2025 study showed for the first time that “human sperm lose their heads upon direct contact” with the parasite.

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