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The Latest Breaking News from Fulcrum

US stocks: Fulcrum shares plummet over 50% after scrapping lead sickle-cell drug on FDA concerns

The oral drug, pociredir, was ‌being tested ⁠to treat sickle-cell ⁠disease, an inherited blood disorder that can trigger pain, anemia and organ damage and reduce life expectancy.

The Economic Times · Jun 2

First ride review: Riding the Look G85 Cezal gravel bike to see if there's a place for an all-rounder in today’s gravel world

Plus riding impressions of Look’s new single sided X-One G gravel pedals

Cycling News · Apr 16

Fulcrum Therapeutics Stock Rally Ignited By Promising Sickle Cell Results

Fulcrum Therapeutics Inc. (NASDAQ:FULC) stock is surging on Monday, after the company released initial results from the ongoing 20 mg dose cohort of the Phase 1b PIONEER trial of pociredir in sickle cell disease.

Benzinga · Dec 8, 2025

From analysis to the latest developments in health,
read the most diverse news in one place.

'Faster than a Tarmac SL8' - Cinelli launches new fastest-ever Aeroscoop road bike

The new Cinelli Aeroscoop uses an aggressive double arm seat stay design to funnel air through the frame

Cycling News · Nov 13, 2025

Is it wheelie October already? New gravel and road hoops dropping everywhere just now

A wheelie good line up from Vision, Miche, Fulcrum and a Dangerholm prototype

Cycling Weekly · Oct 2, 2025

Pinarello takes Dogma off-road with new GR race bike, transitions Grevil to long-haul adventure

Pinarello Dogma GR ignores big tyre clearance in favour of aerodynamics and handling, while Grevil gets... a pannier rack!?

Cycling News · Jul 11, 2025

Fara F/Gravel Bike review: comfortable, versatile, with a good turn of speed

A rugged, trail-ready carbon gravel bike that can be as adventurous as you want it to be

Cycling Weekly · Feb 6, 2025

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Fulcrum Sharq wheelset review: fast aero all-road wheels that are smooth, stable and squiggly

Fulcrum’s aero apex predator laughs in the face of side winds

Cycling Weekly · Sep 8, 2024

Fulcrum expands into trail riding with its new Metal Carbon and ALX wheelsets

Fulcrum's new Metal series wheels are trail tough and compatible with lightweight e-MTBs, but only one is actually made from metal

Bike Perfect · Sep 4, 2024

Fulcrum Rapid Red Carbon gravel wheels perform well and look great

An appealing combination of strength, low weight and smart aesthetics coupled with excellent tubeless performance

Cycling Weekly · Jun 11, 2024

Roval's new hooked wheels cost more than some bikes whilst Fulcrum is sporting wavy rims

New Roval Rapide CLX II Team wheels carry a hefty price and keep their hooked beads

Cycling Weekly · Jun 7, 2024

New Fulcrum Sharq all-road wheel review: Wonderful wavy wheels for big, fast miles

Exceptional in crosswinds, sure-footed downhill, and beautifully silent too

Cycling News · Jun 5, 2024

Fulcrum’s new Sharq wheels claim a 30% improvement in crosswind stability, aim to be the ultimate all-road wheelset

A ‘Two-Wave’ rim profile, all-new spokes, and cup and cone ceramic bearings feature on this top end wheelset

Cycling News · Jun 5, 2024

Advancing Safety and Innovation in Plastic Surgery: The Fulcrum Aesthetics Experience

Fulcrum Aesthetics offers a full spectrum of aesthetic services—from non-invasive treatments like injectables to complex surgical procedures.

Medical Daily · May 29, 2024

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Cycling News · May 1, 2024

Colnago embraces normal standard and makes no aero claims with its new G4-X gravel race bike

New bar, a threaded bottom bracket, and cyclocross heritage create a bike opposed to the heritage-focussed C68 Gravel

Cycling News · Apr 30, 2024

The new Cervelo Aspero gravel bike reduces drag, boosts clearance and gets a threaded bb

The new Aspero frame is also said to exceed ISO frame standards for greater tyre clearances

Bike Perfect · Feb 1, 2024

Colnago C68 Gravel is a carbon lugged, Italian-made gravel bike

Colnago C68 Gravel is built with a modular carbon construction and oozes Italian passion

Cycling Weekly · Jan 17, 2024

Are climbing wheelsets a thing of the past? Fulcrum doesn't think so

The Italian brand launches the Speed 25+, with low profile rims and a claimed weight of under 1,300g

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Bike Perfect · Dec 12, 2023

Berria launches its first Bosch-equipped e-MTB, the Cayman

Berria's new Caymen all-mountain e-MTB features a fancy alloy frame, a large 750Wh battery, and a Bosch Performance Line CX motor

Bike Perfect · Nov 29, 2023

Fulcrum's new flagship Red Zone Carbon+ wheelset gets a new carbon layup for enhanced performance

Fulcrum says the new Red Zone Carbon+ XC/marathon wheelset is lighter, stiffer, and more reactive

Bike Perfect · Jun 20, 2023

Berria Bravo 7 first ride review – a sharp hardtail with a soft touch

Berria’s new Bravo soft tail is a shockless vibration absorbing cross-country race bike

AVNetwork · May 22, 2023

Introducing Fulcrum Immersive

Fulcrum Acoustic acquisition of Venueflex’ DSP and related technologies creates new installation opportunities.

Cycling News · May 3, 2023

Fulcrum rebrands with new, deeper, lighter Speed 57 and 42 wheelsets

Fulcrum ditches the red accents and large logos in favour of subtle stylish silver

Cycling Weekly · May 3, 2023

Fulcrum's new Speed wheelsets are 'wider, lighter and more aero'

The Speed 42 and 57 wheels are 2mm deeper than outgoing models and are designed around 28mm width tires

Birmingham Post · Apr 27, 2023

Jet2 to invest in plant which will turn black bin bags into fuel

The plant is expected to be operational in 2027

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