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The Latest Breaking News from 49ers

49ers injury update: SS Talanoa Hufanga ruled out vs. Cardinals

Talanoa Hufanga is OUT vs. the Cardinals.

USA Today Sports Media Group

49ers star WR has season high in yards after one catch vs. Cardinals

Brock Purdy hit Brandon Aiyuk for a 53-yard gain in the first quarter against the Cardinals in Week 5.

USA Today Sports Media Group

Kyler Murray had top QB speed on TD run in years!

On his 50-yard touchdown run, Kyler Murray reached a top speed of 21.3 miles per hour.

USA Today Sports Media Group

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Kyler Murray astonishingly started to celebrate his touchdown run 44 yards away from the end zone

He KNEW IT right away.

USA Today Sports Media Group

49ers injury news: Jauan Jennings exits after 2 plays vs. Cardinals

The 49ers leading receiver exited on Sunday against the Cardinals after the first two plays of the game.

USA Today Sports Media Group

49ers RB Christian McCaffrey won’t return for TNF vs Seahawks

49ers RB Christian McCaffrey won't return for TNF vs Seahawks

USA Today Sports Media Group

George Kittle, Fred Warner active for 49ers vs. Cardinals

Check out which 49ers players would not suit up against the Cardinals in Week 5.

USA Today Sports Media Group

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Trey McBride, Kelvin Beachum active for Cardinals vs. 49ers

Check out which players for the Cardinals would not suit up against the 49ers.

USA Today Sports Media Group

49ers injury update: George Kittle, Fred Warner active for Week 5

Kittle and Warner are good to go.

USA Today Sports Media Group

What uniforms will Cardinals and 49ers wear in Week 5 matchup?

Check out what uniform combinations the Cardinals and 49ers will wear in their Week 5 showdown.

USA Today Sports Media Group

‘Madden’ simulation predicted Cardinals upset of 49ers

Kyler Murray threw three TD passes, two to Greg Dortch in a 37-27 upset win in a Madden simulation of the Week 5 game.

USA Today Sports Media Group

NFL picks: Cards Wire staff predicts Cardinals-49ers outcome

USA Today Sports Media Group

Trey McBride, George Kittle injury update, availability in Week 5 Cardinals vs. 49ers

ESPN's Adam Schefter gives an update about whether or not Trey McBride and George Kittle will play in Week 5.

USA Today Sports Media Group

49ers Get Encouraging Update on Complicated Christian McCaffrey Injury

McCaffrey has not yet made his 2024 debut for the Niners.

Sports Illustrated

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USA Today Sports Media Group

Cardinals vs. 49ers: The heat is on in Santa Clara Sunday

The unseasonably high temperatures could affect the Cardinals and 49ers in their game on Sunday.

USA Today Sports Media Group

History lesson reveals what makes 49ers’ ground game a consistent success

49ers head coach Kyle Shanahan saw his father find great success with a variety of running backs.

USA Today Sports Media Group

49ers activate one DL off IR, place another DL on IR

49ers roster moves ahead of Week 5:

USA Today Sports Media Group

Cardinals’ practice squad elevations for Week 5 make it look like a starter is out

Check out the two players the Cardinals elevated to the active roster for their game against the 49ers and what the moves mean.

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USA Today Sports Media Group

Trey McBride’s availability in question with rib injury

The Cardinals downgraded him from having no injury designation to being questionable with an injury to his ribs.

USA Today Sports Media Group

49ers prepare for big free agent losses in mock draft

The Notre Dame defensive back was named to the 2024 AP All-American second team.

USA Today Sports Media Group

Cardinals-49ers preview, predictions, picks and best bets

Jess Root and Seth Cox break down the game in Week 5 and make predictions.

USA Today Sports Media Group

NFL picks: ‘H-Bomb’ underdogs continue their hot streak

A look at the performance of big underdogs this season and who are the big underdogs in Week 5.

Sports Illustrated

NFL Denies 49ers' Plea to Switch to White Uniforms Amid Record Santa Clara Heat

San Francisco is scheduled to play in scorching conditions Sunday.

USA Today Sports Media Group

49ers Week 5 injury report: George Kittle, Fred Warner questionable

Lots going on with the 49ers' Week 5 injury report:

USA Today Sports Media Group

Will Trey McBride’s return help jump start Cardinals’ offense?

The Cardinals missed McBride in their Week 4 loss.

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