Gainers
- Pliant Therapeutics, Inc. (NASDAQ:PLRX) jumped 112.6% to $18.88 after the company said its treatment for Idiopathic Pulmonary Fibrosis was well tolerated in a Phase 2a study.
- La Jolla Pharmaceutical Company (NASDAQ:LJPC) gained 80.9% to $6.13 after Innoviva entered into a definitive agreement to acquire the company for $5.95 per share and an incremental $0.28 per share for additional cash proceeds, or an implied enterprise value of approximately $149 million.
- Iterum Therapeutics plc (NASDAQ:ITRM) surged 71.8% to $0.4124 after the company announced that it has reached an agreement with the FDA under the special protocol assessment process on the design, endpoints and statistical analysis of a Phase 3 clinical trial for oral sulopenem etzadroxil-probenecid to begin in Q4.
- Kaspien Holdings Inc. (NASDAQ:KSPN) jumped 39.6% to $3.63.
- Volcon, Inc. (NASDAQ:VLCN) gained 32.5% to $2.1299. Volcon received thousands of non-binding pre-production orders, which, if finalized, would result in more than $70 million worth of revenue following delivery.
- Glory Star New Media Group Holdings Limited (NASDAQ:GSMG) rose 27.7% to $1.1406. Glory Star entered into definitive agreement for going-private transaction.
- ToughBuilt Industries, Inc. (NASDAQ:TBLT) shares gained 22% to $2.4650 after the company announced its Q2 gross sales through Amazon were $3.56 million, representing a 20% year-over-year increase.
- Hillstream BioPharma, Inc. (NASDAQ:HILS) jumped 18.5% to $1.0193. Hillstream BioPharma recently announced a collaboration with Sapien Biosciences in cancer treatments to evaluate the synergy of HSB-1216 with immune checkpoint inhibitors.
- Enveric Biosciences, Inc. (NASDAQ:ENVB) gained 18.5% to $0.2864.
- RedHill Biopharma Ltd. (NASDAQ:RDHL) climbed 17.2% to $1.1494.
- Nortech Systems Incorporated (NASDAQ:NSYS) surged 14.3% to $16.80.
- The Alkaline Water Company Inc. (NASDAQ:WTER) gained 12.7% to $0.53. Alkaline Water recently announced it has identified an estimated $4.5 to $5 million in annual expense reductions and margin enhancements.
- Nyxoah S.A. (NASDAQ:NYXH) gained 11.9% to $8.95 after the company received FDA IDE approval to initiate the ACCCESS study of Genio in complete concentric collapse patients.
- NextNav Inc. (NASDAQ:NN) gained 11.8% to $2.46. NextNav’s10% owner Wocap Global Opportunity Investment Partners LP acquired a total of 19,631 shares at an average price of $2.15.
- Rafael Holdings, Inc. (NYSE:RFL) jumped 11.3% to $2.4041. Rafael Holdings, last month, posted Q3 loss of $0.28 per share.
- Digital World Acquisition Corp (NASDAQ:DWAC) gained 10.7% to $27.14. Shares of Trump Digital business combination partner Digital World Acquisition gained following Friday news Elon Musk is backing away from his proposed Twitter deal.
- Titan Machinery Inc. (NASDAQ:TITN) surged 9.5% to $25.02. Titan Machinery agreed to acquire Heartland Ag Systems for $110 million.
- Phunware, Inc. (NASDAQ:PHUN) gained 9.4% to $1.3350 after gaining 6% on Friday.
- Wah Fu Education Group Limited (NASDAQ:WAFU) surged 8.1% to $2.54. Wah Fu Education Group reported cooperation with Sichuan International Studies University and Dotease Information for online education platform development.
- COMSovereign Holding Corp. (NASDAQ:COMS) gained 7.7% to $0.1939.
- RedHill Biopharma Ltd. (NASDAQ:RDHL) rose 14% to $1.1178.
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Losers
- Aditxt, Inc. (NASDAQ:ADTX) fell 21.3% to $0.1890. Aditxt shares jumped 50% on Friday after the company's Adimune therapeutic program completed a toxicology study indicating a favorable safety profile of ADI-100.
- Freeline Therapeutics Holdings plc (NASDAQ:FRLN) dropped 18% to $0.9094. Freeline Therapeutics announced the presentation of safety and initial efficacy data from the first cohort of the Phase 1/2 B-LIEVE trial for FLT180a for hemophilia B.
- uCloudlink Group Inc. (NASDAQ:UCL) fell 16.9% to $1.1301.
- Aspira Women's Health Inc. (NYSE:AWH) fell 14.6% to $0.8619.
- SeqLL Inc. (NASDAQ:SQL) fell 14.5% to $0.8978.
- ProMIS Neurosciences, Inc. (NASDAQ:PMN) declined 14.3% to $8.14.
- FTC Solar, Inc. (NASDAQ:FTCI) dipped 13.8% to $3.6700.
- Fastly, Inc. (NYSE:FSLY) dropped 13.8% to $11.63 after Morgan Stanley downgraded the stock from Equal-Weight to Underweight and lowered its price target from $18 to $12.
- Connexa Sports Technologies Inc. (NASDAQ:CNXA) declined 12.8% to $0.95.
- Allena Pharmaceuticals, Inc. (NASDAQ:ALNA) fell 12.7% to $0.2009 after gaining 9% on Friday. Allena Pharmaceuticals recently announced rescheduling of special meeting to approve reverse stock split.
- Melco Resorts & Entertainment Limited (NASDAQ:MLCO) dropped 12.5% to $4.8999. The government of Macau has ordered to close shutters on all of its casinos and other commercial establishments in an effort to curb the resurgence of coronavirus outbreak.
- Burning Rock Biotech Limited (NASDAQ:BNR) declined 12.4% to $3.1550.
- Cardlytics, Inc. (NASDAQ:CDLX) fell 12.2% to $16.70.
- Berkeley Lights, Inc. (NASDAQ:BLI) dipped 12% to $5.05.
- Novonix Limited (NASDAQ:NVX) fell 12% to $6.15.
- Pinduoduo Inc. (NASDAQ:PDD) dipped 11.3% to $53.90. Shares of several Chinese companies at large traded lower amid a resurgence in COVID cases which has caused the closure of Macau casinos.
- Opendoor Technologies Inc. (NASDAQ:OPEN) fell 10.5% to $4.97.
- Wynn Resorts, Limited (NASDAQ:WYNN) fell 9.8% to $50.92. Shares of casinos traded lower after Macau announced casino closures amid a resurgence in COVID-19 cases.
- Kiromic BioPharma, Inc. (NASDAQ:KRBP) fell 9.7% to $0.5101. Kiromic BioPharma recently announced the timely completion of construction on its expanded current good manufacturing practice manufacturing facility in Houston.
- Las Vegas Sands Corp. (NYSE:LVS) dipped 9.3% to $31.17. The government of Macau has ordered to close shutters on all of its casinos and other commercial establishments in an effort to curb the resurgence of coronavirus outbreak.
- O-I Glass, Inc. (NYSE:OI) fell 9.2% to $12.24. Barclays downgraded O-I Glass from Equal-Weight to Underweight and lowered the price target from $15 to $13
- Twitter, Inc. (NYSE:TWTR) shares fell 8.3% to $33.77 after Elon Musk on Friday filed to terminate his proposed deal with the company. Wedbush and Baird also lowered their price targets on the stock.
- United Maritime Corporation (NASDAQ:USEA) shares fell 7.3% to $6.95 after gaining 6% on Friday.
- Pinterest, Inc. (NYSE:PINS) fell 7.2% to $18.77.