After a historic 2-1 series win over New Zealand this summer, Ireland have their eyes set on another big win as they take on reigning world champions South Africa in Dublin.
Andy Farrell's side currently top the world rankings but the Springboks will be looking to claim the bragging rights ahead of their meeting in Pool B at next year's World Cup in France.
It will be a special day for Ireland regardless of the result, with scrum-half Conor Murray winning his 100th cap while veteran Johnny Sexton becomes his country's fifth most-capped player at the age of 37. The pair are two of the five host players who started the last game between these two sides in 2017, which ended 38-3 to Ireland in a convincing display.