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Total Film
Total Film
Entertainment
Amy West

The Supe-killing virus in The Boys season 5 explained, from its Gen V origins to theories on how Homelander can survive it

Frenchie with the Supe Virus in The Boys season 5.

The Boys season 5 has officially kicked off, and the titular team has one objective in the Prime Video show's final chapter: kill Homelander. Given that he's the most powerful Supe in the world and has the backing of the US government now, though, it's not going to be an easy task.

If you've seen the two-episode premiere (caution: spoilers to follow!), you'll know that Billy Butcher (Karl Urban), Annie (Erin Moriarty) and co are planning on using a Supe-killing virus to take out the milk-guzzling villain. But there's one issue; it's not strong enough – so they've brought in R&D researcher Dr. Sameer Shah (Omid Abtahi) to pimp up its potency.

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