West Ham United boss David Moyes has named his side to face Gent at the Ghelamco Arena.
The Hammers will look to make it 11 wins out of 11 in the Europa Conference League this season when they face the Buffalos in the first leg of their quarter-final tie.
As the Irons look to take a first leg advantage back to the London Stadium, Moyes has made six changes to face Gent from the side that recorded a 1-0 victory over Fulham on Sunday.
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In what appears to be a switch to a 3-5-2 formation, Alphonse Areola comes back into the side in goal, continuing his record as one of only two players to start all 11 games in Europe this season.
Ben Johnson and Nayef Aguerd both come into the starting 11 and play alongside Angelo Ogbonna in the back three, with Emerson coming in at left wing-back and Vladimir Coufal keeping his place on the right.
Manuel Lanzini, like Areola, makes his 11th European start of the season in a midfield three with Declan Rice and Flynn Downes.
Danny Ings starts up front in his first European start since October 2015 in the Europa League for Liverpool, playing alongside Jarrod Bowen.
Midfielder Lucas Paqueta is back in the squad after missing the trip to Craven Cottage with a minor foot injury, he only makes the bench and is joined by teenage striker Divin Mubama. Lukasz Fabianski, Kurt Zouma, Aaron Cresswell, Tomas Soucek, Pablo Fornals and Michail Antonio also drop to the bench.
Italian striker Gianluca Scamacca remains sidelined with a knee injury which has kept him out of the last two games.
Meanwhile, Gent boss Hein Vanhaezebrouck has made three changes from the side that drew 1-1 with Union Saint-Gilloise in the Belgian Pro League on Saturday.
West Ham United starting XI: Alphonse Areola; Ben Johnson, Angelo Ogbonna, Nayef Aguerd; Vladimir Coufal, Flynn Downes, Declan Rice, Manuel Lanzini, Emerson; Jarrod Bowen, Danny Ings
Substitutes: Lukasz Fabianski, Joseph Anang, Thilo Kehrer, Kurt Zouma, Aaron Cresswell, Tomas Soucek, Pablo Fornals, Lucas Paqueta, Said Benrahma, Maxwel Cornet, Divin Mubama, Michail Antonio
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