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Emma Thomson, Clinical Professor of Infectious Diseases and Associate Director, MRC-Centre for Virus Research, University of Glasgow

We investigated the cause of an unexplained outbreak of hepatitis in children in the UK – here's what we found

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In the spring of 2022, a paediatric gastroenterologist treating children in the Queen Elizabeth University Hospital in Glasgow issued an alert to Public Health Scotland (PHS), warning of an unusual outbreak of hepatitis cases in her clinic.

Hepatitis refers to inflammation of the liver, and is usually caused by viral infections, toxins (including alcohol), medications, autoimmune conditions or inherited conditions. Hepatitis is unusual in children and when it does occur, cases are generally isolated.

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