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The Guardian - UK
The Guardian - UK
Science
Hannah Devlin Science correspondent

US scientists create most comprehensive circuit diagram of mammalian brain

Digital representation of neurons in a section of a mouse's brain
A digital representation of neurons in a section of a mouse's brain. Photograph: Forrest Collman/Allen Institute/AP

The most comprehensive circuit diagram of neurons in a mammalian brain has been created by scientists, providing groundbreaking insights into the mystery of how the brain works.

The map is of a speck of a mouse’s visual cortex, smaller than a grain of sand, and traces the structure of 84,000 neurons linked by half a billion synapses and approximately 5.4km of neuronal wiring. The 3D reconstruction of the cubic millimetre of brain is helping uncover how the brain is organised and how different cell types work together, and could have implications for the understanding of intelligence, consciousness and neuronal conditions such as Alzheimer’s, Parkinson’s, autism and schizophrenia.

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