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Salon
Salon
Science
Nicole Karlis

Understanding the brain's sewage system

It's well-documented that genetics play a role in the risk of developing Alzheimer's disease (AD), a brain disorder that causes dementia through damage to brain cells and other changes in the brain. Age is a risk factor, too. Worldwide, an estimated 55 million people have the condition, and 500,000 new cases are diagnosed in the U.S. each year. Yet despite this knowledge, there hasn’t been as much progress as hoped to treat and reverse the devastating and ultimately fatal symptoms of cognitive decline caused by the disease. 

Currently, available treatments temporarily improve symptoms of memory loss and issues with thinking and reasoning. However, they don’t entirely stop the underlying decline and death of brain cells.

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