A Danish study has found that girls exposed to paracetamol during pregnancy had differences in reproductive development, with those exposed before 17 weeks having an average ovarian volume around 40 per cent smaller than girls whose mothers did not use the painkiller.
Published in Human Reproduction Open, the study examined 302 three-month-old girls whose mothers' paracetamol use had been tracked during pregnancy. Researchers also found about 23 per cent fewer ovarian follicles among girls exposed from 17 weeks onwards, although the observational research cannot establish that paracetamol caused the differences.