Toulouse and Nice will feature in the hat on Thursday for the draw for the semifinals of the Coupe de France following penalty shootout wins over Marseille and Lorient respectively.
At Marseille's Vélodrome on Wednesday night, Toulouse drew 2-2 with the home team after extra time.
But they won the penalty shootout 4-3 to hand a blow to the new Marseille boss Habib Beye.
"The disappointment is equal to the hope that was placed in us in the Coupe de France," said Beye. "We have to accept it, look ahead, face up to it, accept the sadness of the supporters and not question the disappointment."
Paris Saint-Germain have won the Coupe de France eight times in the past 11 seasons and their elimination in the last 32 of the competition to Paris FC in January offered the remaining clubs a chance of silverware.
Marseille, who have not lifted the trophy since 1989, were among the favourites to take the crown.
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But they twice squandered the lead during the game against fellow Ligue 1 outfit Toulouse.
Leonardi Balerdi and Ethan Nwaneri missed their spot kicks in the shootout.
"I will always praise a player who takes a penalty in those situations," said Beye. "Balerdi and Nwaneri are the most affected after the match. There is sadness."
Beye, a former Marseille player, said the side would target one of the spots leading to the 2026/2027 Champions League.
With 10 games remaining in Ligue 1, Marseille occupy fourth place – a berth leading to the qualifying stages for next season's Champions League.
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"Obviously we're disappointed but we have to put it behind us," added Beye.
"My job will be to give the players the energy to go into battle again against Toulouse. We were on top throughout the game but perhaps we lacked a touch of technical skill."
Following a 0-0 draw against a Lorient side reduced to 10 men from the 44th minute, Nice claimed the penalty shootout 6-5.
On Tuesday night, Strasbourg progressed to the last four following a 2-1 victory over second-division Reims.
On Thursday night, an all Ligue 1 clash between Lyon and Lens will provide the last team for the semifinals.
