Tottenham boss Antonio Conte has opted to stick with the forward line which served him well last week as Richarlison again starting alongside Son Heung-min and Harry Kane.
Dejan Kulusevsku sits on the bench while Eric Dier, as expected, gets the nod against his former side.
Brazil forward Richarlison has hit red-hot form recently after starting most of the season on the bench, scoring twice against Marseille last week.
It has forced Conte to consider breaking up his front-three from last season - Kulusevski, Son Heung-min and Harry Kane - that proved so effective.
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“For sure I think every manager likes this kind of problem,” he said. “It means up front we have four players for three places.
“We are in the right way because to face four competitions, especially if you are to play in the Champions League, you need to have a deep squad.
“At the moment we have four players and everyone deserves to play. We started with Sonny, Harry and Decky, then the last games I prefer to give the possibility to Richy to play.
“For sure I have the possibility to pick up three important players and know that I have another player on the bench who is ready to come on and help us, like in the last game against Marseille.”
Spurs only have one injury worry ahead of the game, with Lucas Moura still out injured.
Confirmed team news
Sporting XI: Adan, Inacio, Coates, Matheus Reis, Porro, Morita, Ugarte, Nuno Santos, Trincao, Edwards, Goncalves
Subs: Alexandropoulos, Israel, Rochinha, Issahaku, Paulinho, Andre Paulo, Arthur Gomes, Ricardo Esgaio, Marsa, Nazinho
Tottenham XI: Lloris, Romero, Dier, Davies, Emerson, Hojbjerg, Bentancur, Perisic, Richarlison, Son, Kane
Subs: Doherty, Skipp, Sanchez, Gil Salvatierra, Sessegnon, Forster, Kulusevski, Spence, Tanganga, Bissouma, White, Lenglet
Injured: Moura (leg)