Diogo Dalot and Lisandro Martinez could return to the Manchester United squad for their first Premier League game of the year at home to Bournemouth.
Dalot has missed the last three games due to a hamstring injury he sustained in Portugal's World Cup quarter-final defeat to Morocco but he started training last week.
Martinez, absent for the wins over Burnley, Nottingham Forest and Wolves through his involvement in Argentina's triumph in Qatar, has also had multiple training sessions.