Alternate tunings can be a gateway to creative ideas and new textures, but they often require re-orienting yourself with the fretboard. Nashville tuning, however, requires no such effort, as you can replicate anything you play in standard tuning.
There is one caveat: you have to restring the guitar in order to get this tuning. In practice, it’s not hard at all – you start with a 12-string set and use the higher octave sixth, fifth, fourth and third strings in place of your standard gauge strings. The first and second strings remain the same.