Walk down any grocery store aisle today, and you will notice subtle changes in what fills shoppers’ carts. Americans using GLP-1 weight loss and diabetes medications are fundamentally altering how they buy food. With one in five U.S. households now including a current medication user, appetite-suppressing drugs are rewriting consumer habits. Grocery spending per household has dropped noticeably as buyers focus on smaller quantities and better nutrition. Supermarkets and manufacturers are scrambling to adapt to a customer base that values entirely different products than they did a few years ago.