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The Chan Zuckerberg Initiative cut 70 jobs as the Meta CEO’s philanthropy goes all in on mission to 'cure or prevent all disease'

Mark Zuckerberg Meta the Chan Zuckerberg Initiative BioHub CZI Disease Philanthropy Priscilla Chan

Priscilla Chan and Mark Zuckerberg (Credit: Getty Images—Taylor Hill)

The Chan Zuckerberg Initiative is making big changes, and it started 2026 with some job cuts to recalibrate and refocus its efforts on AI-powered biomedical research.

The philanthropic organization, formed by Meta cofounder and CEO Mark Zuckerberg and his wife, Dr. Priscilla Chan, is cutting about 70 jobs, or roughly 8% of its workforce, a CZI spokesperson confirmed to Fortune. The layoffs happened primarily at the organization’s Redwood City headquarters in San Mateo, Calif.

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