The 2022 Super League season may only be two weeks old but some clubs are already struggling on the injury front.
Throw in other availability issues and it is a tough time for several clubs including Leeds Rhinos.
Here, Rugby League Live takes a look at the current list of unavailable players and those who are touch and go for round three.
Castleford Tigers
Ruled out: Callum McLelland (knee), Jacques O’Neill (hamstring), Sosaia Feki (Achilles), Danny Richardson (neck)
Doubtful: Nathan Massey (hip), Adam Milner (back), Kenny Edwards (calf), Alex Sutcliffe (throat), Jake Mamo (head)
Catalans Dragons
Ruled out: Arthur Mourgue (ankle), Julian Bousquet (arm), Mickael Goudemand (concussion), Dylan Napa, Gil Dudson (both suspension)
Doubtful:
Huddersfield Giants
Ruled out: Jack Cogger, Jake Wardle (both ankle)
Doubtful:
Hull FC
Ruled out: Scott Taylor (foot), Manu Ma’u (hamstring), Joe Cator (Achilles), Kane Evans, Andre Savelio (both suspension)
Doubtful: Carlos Tuimavave (hamstring)
Hull KR
Ruled out: Ben Crooks (knee), Luis Johnson (foot), Will Maher (eye socket), Albert Vete (suspension)
Doubtful: Lachlan Coote (hamstring), Will Dagger (shoulder), Rowan Milnes (ankle)
Leeds Rhinos
Ruled out: Tom Holroyd (ankle), Richard Myler (groin), James Bentley (suspension), Sam Walters (shoulder), Muizz Mustapha (unspecified), Rhyse Martin (family bereavement)
Doubtful: Harry Newman (hamstring), Ash Handley (hip), Cameron Smith (back)
Salford Red Devils
Ruled out: Harvey Livett (wrist), Kallum Watkins (knee)
Doubtful:
St Helens
Ruled out: Regan Grace (elbow)
Doubtful: Will Hopoate (rib)
Toulouse Olympique
Ruled out: Mathieu Jussaume (broken leg)
Doubtful: Latrell Schaumkel, Harrison Hansen, Paul Marcon (all unspecified), Dominique Peyroux (groin), James Cunningham (hamstring)
Wakefield Trinity
Ruled out: Bill Tupou, Lee Kershaw, Jack Croft (all knee), Lee Gaskell (elbow), Reece Lyne (suspension)
Doubtful: Mason Lino, Jacob Miller (both unspecified), David Fifita (leg and thumb)
Warrington Wolves
Ruled out: Billy Magoulias (ankle), Greg Minikin, James Harrison (both knee), Oliver Holmes (suspension)
Doubtful: Mike Cooper (illness), Connor Wrench (back)
Wigan Warriors
Ruled out: Ethan Havard (back), Iain Thornley (ankle)
Doubtful: