
Washington [US]: Researchers at the University of Colorado Anschutz Medical Campus and their international collaborators have discovered that a protein critical in the embryonic stages of life is reactivated in certain cases of mesothelioma, offering clues into the origin of this aggressive cancer. The study was published in the journal Nature Communications.
"Together with our basic research and clinical collaborators, we have discovered that in numerous mesothelioma tumours, the Hand2 protein has been turned back on, possibly altering the cells of the tumour," said Christian Mosimann, lead author of the study and associate professor of paediatrics in the section of developmental biology at the University of Colorado School of Medicine on the CU Anschutz Medical Campus.