The Chargers and Bills are set to square off this Saturday.
Here’s how Los Angeles and Buffalo stack up statistically ahead of the Week 16 matchup:
Offense
| Category | Rank | Stat |
| Points per game | 21.6 (17th) | 27.1 (6th) |
| Passing offense | 238.0 (10th) | 244.6 (8th) |
| Rushing offense | 95.7 (27th) | 132.3 (6th) |
| Total offense | 333.7 (15th) | 376.9 (4th) |
| 3rd down conversions | 40.41% (14th) | 49.16% (1st) |
| Red zone scoring | 65.00% (4th) | 67.31% (3rd) |
| Sacks allowed | 34 (T-14th) | 19 (1st) |
| Turnovers | 19 (T-16th) | 21 (T-21st) |
Defense
| Category | Rank | Stat |
| Points allowed | 24.6 (27th) | 18.1 (4th) |
| Passing defense | 261.4 (30th) | 200.6 (9th) |
| Rushing defense | 113.9 (18th) | 112.2 (15th) |
| Total defense | 375.3 (29th) | 312.9 (12th) |
| 3rd down conversions | 37.57% (14th) | 39.23% (19th) |
| Red zone defense | 55.56% (17th) | 53.49% (14th) |
| Sacks | 44 (6th) | 46 (T-4th) |
| Takeaways | 17 (T-20th) | 24 (T-3rd) |
