South Australia has recorded 2,503 new cases and one COVID-linked death, the day before significant restrictions are scrapped.
SA Health said a man in his 70s died.
Case numbers have hovered around 2,500 for the past few days, and active cases are now at 22,054.
However, the number of people in hospital has continued to decrease and now sits at 88.
There are 10 people in intensive care and two requiring a ventilator.
SA Health said its regular genome sampling of COVID cases showed that 100 per cent were the Omicron variant.
SA will further relax COVID rules tomorrow, taking the state to its most relaxed level of restrictions since the pandemic arrived.
The changes come as the Omicron sub-variant BA.2 raises concerns interstate.
The variant has also been detected in South Australia, but Police Commissioner and State Emergency Coordinator Grant Stevens told ABC Radio Adelaide this morning that he had not received any specific advice from SA Health.
"It hasn't been brought to my attention as a variant of concern or any indication that the arrival of this sub-variant is going to change our current situation in terms of how we're managing COVID," he said.
"I suppose as a contrast, when Omicron first emerged there was urgent discussions and meetings held about the possible implications of this new variant and we have not had that at this point in time.
South Australian epidemiologist Adrian Esterman said there was reason to be concerned about the Omicron sub-variant BA-2.
He said while research showed the sub-variant had the same rate of hospitalisations and ability to evade the immune systems as BA-1, because it was more transmissible, there would be more cases and therefore more hospitalisations.
According to the latest genome sampling from SA Health, about one in five cases in South Australia are BA-2.
Professor Esterman said the sub-variant would become the dominant strain in SA.
"A couple of weeks ago it was about 10 per cent of Australian cases, today it's about 25 per cent of Australian cases, and in a couple of weeks' time it's probably going to be 100 per cent of Australian cases," he said.
However, Immunisation Coalition chair Dr Rod Pearce told ABC Radio Adelaide's David Bevan he had spoken about the new sub-variant with interstate colleagues, and they believed the current vaccines offered enough protection against it.
"We're still happy with the coverage and we're still happy our treatments are working," he said.