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The Conversation
The Conversation
Kevin Naidoo, Professor of Scientific Computing and Physical Chemistry, University of Cape Town

South African scientists make breakthrough in decoding cancer’s most effective survival strategy

In the intricate biology of the human body, organs such as the breast, the colon and the lungs are lined with a defensive barrier known as the epithelium. At the heart of this barrier sits a remarkable protein called Mucin-1 (MUC1). In a healthy body, MUC1 is like a sentinel.

It stands on the cell wall, draped in a complex “armour” of long chains of sugar molecules (carbohydrates), where it serves as a physical shield against bacteria, viruses and toxins. Crucially, it communicates with the immune system, telling our natural defences when the body is under threat.

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