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Evening Standard
Evening Standard
Lifestyle
Georgie Lucas

Sirtuin 6: This under-the-radar protein could be the key to longevity

Humanity’s perennial quest has been for the fountain of youth — long before healthspans, biohacking and longevity became buzzwords. It’s a search that has taken on a precise focus as scientific research — and breakthroughs — have started to deliver tangible possibilities. NAD+ and NMN are already familiar names in the longevity lexicon, but now sirtuins are moving into the spotlight.

These seven protein enzymes found in our cells regulate cellular health, metabolism, stress and ageing. They become less active, and therefore less effective, as we age, slowing our repair systems, impacting energy production and impairing cellular defence.

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