Primary dengue virus infections constitute a substantial fraction of severe disease cases and fatalities, states a new published study questioning the currently widely held belief that severe dengue disease is mainly due to secondary dengue infections.
Dengue is a viral infection caused by the dengue virus (DENV), transmitted to humans through the bite of infected mosquitoes.
Patients who are infected by any DENV for the first time are known as cases of primary dengue infection. Patients who were previously infected by another DENV and then present with infection from a new serotype are known as cases of secondary dengue infection.