'Significant Flare-Up' in Palisades Fire Prompts New Evacuation Orders

Smoke and flames from the Palisades Fire light up the night sky in the Encino neighborhood of Los Angeles. (Credit: AGUSTIN PAULLIER/AFP via Getty Images)

A "significant flare-up" in the largest of the six wildfires scorching Southern California prompted new evacuation orders, but the fierce winds that have spread the flames calmed Friday night, giving weary firefighters a short respite.

The Palisades Fire, the largest inferno that has burned 21,317 acres and destroyed thousands of homes and businesses, has shifted direction and new evacuation orders were issued for the Brentwood neighborhood and the foothills of the San Fernando Valley, the Los Angeles Times reported.