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Medical Daily
Medical Daily
Joseph James

Shrinking Rooms, Warping Time: An Asthma Pill Shows the Strongest Drug Signal for Alice in Wonderland Syndrome

Alice in Wonderland syndrome makes the world look wrong. Objects can seem to shrink or swell, time can speed up or drag, and a person's own body can feel the wrong size. The condition is most often tied to migraine and infections, but an analysis of global drug-safety reports points to another possible trigger: some everyday medications.

French researchers combed through VigiBase, the World Health Organization's global database of suspected drug side effects, and found 87 reports of Alice in Wonderland syndrome linked to medicines. Montelukast, a widely prescribed asthma and allergy pill sold under the brand name Singulair, produced the strongest statistical signal in both children and adults. The study was published online in December 2025 in Psychiatry Research.

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