Scientists have described a molecular switch that appears to determine where infection-fighting white blood cells travel inside the body, and, equally important, when they hold still.
The work, published in Science Advances and announced July 30, comes from a collaboration between Professor Randy Mrsny at the University of Bath's Center for Drug Discovery and Professor Beth McCormick at UMass Chan Medical School. It concerns neutrophils, the most abundant white blood cells in circulation and the first immune cells to arrive at an infection.