
Washington [US]: Huntington's disease (HD) is a genetic brain disorder caused by a mutation in the huntingtin gene. It is a neurological disease that has no cure and produces personality changes, dementia symptoms, and uncontrollable convulsive movements, eventually leading to death.
Such HD symptoms are known to be produced by the loss of brain cells in the striatum as a result of difficulties emerging in synapses that are critical to brain function during the disease's progression. However, the precise mechanism behind brain dysfunction during the course of HD is still unknown. The findings of the study were published in the journal Acta Neuropathologica.