Ahead of this mammoth fixture in the Europa League we look at the best available combined 11 from the two sides for tonight.
The sides meet at the Camp Nou for the first leg of their Europa League play-off, as they both seek a place in the last 16. They both enter the game having had strong opening halves to their domestic league campaigns.
Barcelona top La Liga, with an eight-point cushion over Real Madrid. Man United meanwhile are third in the Premier League, five points behind table-topping, Manchester City.