It comes amid team owner/driver Frits van Eerd's involvement in a money laundering case in the Netherlands that came to light earlier this month.
Van Eerd was reportedly arrested in connection with the case, only to be released days later, but he remains a suspect and has stepped down from his position as CEO of supermarket chain Jumbo, whch sponsors RTN.
The Dutch outfit was due to race at Road Atlanta this weekend as part of its attack on IMSA's Michelin Endurance Cup, which also comprises the Rolex 24 at Daytona, Mobil 1 Twelve Hours of Sebring and Sahlen's Six Hours of the Glen.
Van Eerd was again due to share the RTN Oreca 07-Gibson with ex-Formula 1 racer Giedo van der Garde and Dylan Murry.
RTN confirmed its withdrawal in a short statement posted on Twitter on Tuesday.
It read: "Following Frits van Eerd's decision to focus on his personal situation in the coming period, Racing Team Nederland will not participate in the IMSA race this weekend in Atlanta.
"We understand and respect his decision and guarantee him our support."
Van Eerd, van der Garde and Murry had run second in the Michelin Endurance Cup points standings in the LMP2 class, behind PR1/Mathiasen Motorsports trio Ben Keating, Mikkel Jensen and Scott Huffaker, having finished second at both Daytona and Sebring and then third at Watkins Glen.
Tower Motorsport's John Farano leads the overall LMP2 standings by 23 points from Era Motorsport pair Ryan Dalziel and Dwight Merriman.