In the 18th century, physicians noticed nuns had some of the highest rates of breast cancer. It was one of the earliest clues that led scientists to suspect that child-bearing and breastfeeding could protect against the disease.
Modern data has confirmed the centuries-old observation but the biological reasons behind it have remained unclear. Explanations have often focused on pregnancy-related hormonal changes, but research published Tuesday in Nature has found breastfeeding provides long-lasting immune protection.