Anthony Albanese's trip to Washington comes at a time of heightened security tensions across the globe and challenging conditions for the Australian economy.
The official visit next week is expected to include a state dinner at the White House with a host of celebrity guests and a bilateral meeting with US President Joe Biden.
The prime minister and president were due to meet in Sydney in May, with a side trip by the US leader to address parliament in Canberra, but domestic political pressures kept Mr Biden from travelling.