
The Chronicle of Philanthropy’s annual list of the biggest charitable donations from individuals or their foundations totaled $5 billion in 2025. Topping the list was $2 billion from Nike co-founder Phil Knight and his wife, Penny, followed by a $746.7 million donation from Warren Buffett and a $500 million pledge from the mother and stepfather of Amazon founder Jeff Bezos.
Nearly 40% of the $5 billion total came from the Knights’ gift to Oregon Health & Science University. More than $1.3 billion, or about one-quarter of the total, came from four donations to Buffett family foundations.