Get all your news in one place.
100's of premium titles.
One app.
Start reading
Marie Claire
Marie Claire
Lifestyle
Lucy Abbersteen

PDRN Serums Are Everywhere—But Are They Actually Worth The Hype? Two Leading Skin Doctors Explain

Lilian Litehiser seen wearing Beaumont white fake fur midi coat, white cotton top, Topshop grey pinstripe micro shorts, black leather / gold belt and Massimo Dutti black suede leather clutch bag, during Berlin Fashion Week AW25 on January 31, 2025 in Berlin, Germany.

In popular culture and on social media, you can barely move for mention of ‘salmon sperm’ injections and facials at the moment. (This nickname is actually slightly inaccurate, but I’ll get to that later.) Kim Kardashian is getting them, the Selling Sunset girls are celebrating Galentine’s with them. And, yes, the beauty and aesthetics industries have been abuzz with the power of injectable polynucleotides, with both beauty editors and consumers having been impressed by the results.

After the initial polynucleotide boom, a secondary trend began to emerge on social media: PDRN serums, also acquiring the nickname salmon sperm skincare. And take to TikTok and you'll see that people are, ostensibly, loving said serums. But if there’s one thing I’ve learned about skincare results in my years as a beauty editor, it’s that no topical skincare product can achieve results that are close to those of an injectable treatment—which are the reason so-called salmon and trout sperm-derived treatments really took off in the first place.

Sign up to read this article
Read news from 100's of titles, curated specifically for you.
Already a member? Sign in here
Related Stories
Top stories on inkl right now
One subscription that gives you access to news from hundreds of sites
Already a member? Sign in here
Our Picks
Fourteen days free
Download the app
One app. One membership.
100+ trusted global sources.